Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7160, USA.
J Anxiety Disord. 2011 Jun;25(5):727-30. doi: 10.1016/j.janxdis.2011.03.010. Epub 2011 Mar 24.
We explore comorbidity of anorexia nervosa (AN) and generalized anxiety disorder (GAD) and their relation with body mass index (BMI) and evaluate the presence of fasting and excessive exercise which both have anxiolytic and weight loss effects. All participants were female: 32 with AN only, 607 with GAD only, 22 with AN and GAD (AN+GAD), and 5424 with no history of AN or GAD (referent) from the Swedish Twin study of Adults: Genes and Environment (STAGE). Lowest adult BMI differed significantly (p<.001) and was lower in those with AN+GAD than those with AN only (p<.029). Those with AN+GAD were most likely to endorse fasting and excessive exercise, followed by women with AN only, women with GAD only, and the referent. Comorbid AN and GAD may be a particularly pernicious presentation influencing both BMI and proclivity to engage in behaviors such as fasting and exercise that serve both weight loss and anxiolytic goals.
我们探讨了神经性厌食症(AN)和广泛性焦虑症(GAD)的共病情况及其与体重指数(BMI)的关系,并评估了禁食和过度运动的存在,这两者都具有抗焦虑和减肥的效果。所有参与者均为女性:32 名仅患有 AN,607 名仅患有 GAD,22 名同时患有 AN 和 GAD(AN+GAD),5424 名无 AN 或 GAD 病史(参照组),来自瑞典成人双胞胎研究:基因与环境(STAGE)。成人 BMI 最低值差异显著(p<.001),且 AN+GAD 组明显低于仅 AN 组(p<.029)。AN+GAD 组最有可能禁食和过度运动,其次是仅 AN 组、仅 GAD 组和参照组。同时患有 AN 和 GAD 可能是一种特别有害的表现,会同时影响 BMI 和进行禁食和运动等行为的倾向,这些行为既可以达到减肥的目的,也可以达到抗焦虑的目的。