微管末端结合：EB 感知鸟嘌呤核苷酸状态。
Microtubule end binding: EBs sense the guanine nucleotide state.
机构信息
Cell Biology, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands.
出版信息
Curr Biol. 2011 Apr 26;21(8):R283-5. doi: 10.1016/j.cub.2011.03.023.
PMID:21514511
Abstract
EB proteins accumulate at the tips of growing microtubules and recruit to them a multitude of factors to regulate microtubule functions. A new study suggests that EBs recognize microtubule ends by distinguishing between different states of the tubulin-bound guanine nucleotide.
摘要
EB 蛋白聚集在生长中的微管末端，并招募大量因子来调节微管功能。一项新的研究表明，EB 蛋白通过区分结合了鸟嘌呤核苷酸的微管的不同状态来识别微管末端。
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