Biaggi Patric, Carasso Shemy, Garceau Patrick, Greutmann Matthias, Gruner Christiane, Tsang Wendy, Rakowski Harry, Agmon Yoram, Woo Anna
Division of Cardiology, Peter Munk Cardiac Program, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Echocardiography. 2011 May;28(5):539-47. doi: 10.1111/j.1540-8175.2011.01386.x. Epub 2011 Apr 24.
Echocardiographic speckle tracking strain has gained clinical importance. However, the comparability of measurements between different software systems is not well defined.
In 47 healthy subjects left ventricular (LV) two-dimensional (2D) peak strain and time to peak strain (TTP) generated by EchoPAC (2DS) and velocity vector imaging (VVI) were compared. For each type of strain (longitudinal [LS], circumferential [CS], and radial strain [RS]) we compared global, anatomical level and segmental values.
When comparing 2DS to VVI, Pearson correlation coefficients (r) of global LS, CS, and RS were 0.68, 0.44, and 0.59, respectively (all P < 0.05). Correlation of global TTP was higher: 0.81(LS), 0.80 (CS), and 0.68 (RS), all P < 0.01. Segmental peak strain differed significantly between 2DS and VVI in 8/18 (LS), 17/18 (CS), and 15/18 (RS) LV segments (P < 0.05). However, segmental TTP significantly differed only in 5/18 (LS), 7/18 (CS), and 4/18 (RS) of LV segments. Similar strain gradients were found for both systems: apical strain was higher than basal and midventricular strain in LS and CS, with a reversed pattern for RS (P < 0.05).
TTP strain as well as strain gradients were comparable between VVI and 2DS, but most peak strain values were not. The software-dependency of peak strain values must be considered in clinical application. Further studies comparing the diagnostic and prognostic accuracy of strain values generated by different software systems are mandatory.
超声心动图斑点追踪应变已在临床上具有重要意义。然而，不同软件系统之间测量值的可比性尚未明确界定。
比较了47名健康受试者由EchoPAC（2DS）和速度向量成像（VVI）生成的左心室（LV）二维（2D）峰值应变和峰值应变时间（TTP）。对于每种应变类型（纵向应变[LS]、圆周应变[CS]和径向应变[RS]），我们比较了整体、解剖水平和节段值。
将2DS与VVI进行比较时，整体LS、CS和RS的Pearson相关系数（r）分别为0.68、0.44和0.59（均P<0.05）。整体TTP的相关性更高：0.81（LS）、0.80（CS）和0.68（RS），均P<0.01。2DS和VVI之间，8/18（LS）、17/18（CS）和15/18（RS）个LV节段的节段峰值应变存在显著差异（P<0.05）。然而，节段TTP仅在5/18（LS）、7/18（CS）和4/18（RS）个LV节段存在显著差异。两个系统发现了相似的应变梯度：在LS和CS中，心尖应变高于基底和心室中部应变，RS则相反（P<0.05）。
VVI和2DS之间TTP应变以及应变梯度具有可比性，但大多数峰值应变值不具有可比性。在临床应用中必须考虑峰值应变值的软件依赖性。必须开展进一步研究比较不同软件系统生成的应变值的诊断和预后准确性。
