Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Laryngoscope. 2011 May;121(5):990-3. doi: 10.1002/lary.21419.
The introduction of the pedicled nasoseptal flap (NSF) has decreased postoperative cerebrospinal fluid (CSF) leak rates from >20% to <5% during expanded endoscopic skull base surgery. The NSF must be raised at the beginning of the operation to protect the posterior pedicle during the expanded sphenoidotomy. However, in most pituitary tumor cases, an intraoperative CSF leak is not expected but at times encountered. In these cases, a "rescue" flap approach can be used, which consists of partially harvesting the most superior and posterior aspect of the flap to protect its pedicle and provide access to the sphenoid face during the approach. The rescue flap can be fully harvested at the end of the case if the resultant defect is larger than expected, or if an unexpected CSF leak develops. This technique minimized septum donor site morbidity for those patients without intraoperative CSF leaks.
The rescue flap technique allows for binaural and bimanual access to the sella without compromise of the pedicle during the extended sphenoidotomies and tumor removal. If an intraoperative CSF leak is encountered, the rescue flap is then converted into a normal nasoseptal flap for skull base reconstruction. If no leak is obtained, then the patient does not suffer additional donor site morbidity from the full flap harvest.
This new technique allows for sellar tumor removal prior to the nasoseptal harvest, thereby eliminating donor site morbidity for those pituitary tumor patients who do not have an intraoperative CSF leak.
带蒂鼻中隔鼻瓣(NSF)的引入,将扩大经鼻内镜颅底手术中术后脑脊液(CSF)漏的发生率从>20%降低到<5%。NSF 必须在手术开始时抬起,以在扩大蝶窦切开术期间保护后蒂。然而,在大多数垂体瘤病例中,预计不会发生术中 CSF 漏,但有时会遇到。在这些情况下,可以使用“抢救”瓣方法,包括部分收获瓣的最上和后部分,以保护其蒂,并在接近时提供进入蝶骨面的通道。如果最终缺损大于预期,或者如果发生意外的 CSF 漏,则可以在手术结束时完全收获抢救瓣。这种技术使那些术中没有 CSF 漏的患者鼻中隔供区的发病率最小化。
抢救瓣技术允许在不影响延长蝶窦切开术和肿瘤切除时的蒂的情况下,对双侧和双侧进行蝶鞍的进入。如果术中发生 CSF 漏,则将抢救瓣转换为用于颅底重建的正常鼻中隔瓣。如果没有获得泄漏,则患者不会因全瓣收获而遭受额外的供区发病率。
这项新技术允许在鼻中隔瓣采集之前进行鞍内肿瘤切除术,从而消除了那些术中没有 CSF 漏的垂体瘤患者的供区发病率。