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使用生物传感器测定抗氧化剂清除自由基的能力。

Determination of the antioxidants' ability to scavenge free radicals using biosensors.

机构信息

BIOMEM Group, Centre of Phytopharmacy, University of Perpignan, France.

出版信息

Adv Exp Med Biol. 2010;698:222-33. doi: 10.1007/978-1-4419-7347-4_16.

Abstract

Free radicals are highly reactive molecules generated during cellular metabolism. However, their overproduction results in oxidative stress, a deleterious process that can damage cell structures, including lipids and membranes, proteins and DNA. Antioxidants respond to this problem, scavenging free radicals. This chapter critically reviews the electrochemical biosensors developed for the evaluation of the antioxidant capacity of specific compounds. Due to the ability of these devices to perform simple, fast and reliable analysis, they are promising biotools for the assessment ofantioxidant properties.

摘要

自由基是细胞代谢过程中产生的高反应性分子。然而,它们的过度产生会导致氧化应激,这是一种有害的过程,会损害细胞结构,包括脂质和膜、蛋白质和 DNA。抗氧化剂可以应对这个问题,清除自由基。本章批判性地回顾了为评估特定化合物的抗氧化能力而开发的电化学生物传感器。由于这些设备具有进行简单、快速和可靠分析的能力,因此它们是评估抗氧化特性的有前途的生物工具。

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