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10 -（2 - 羟乙基）- 9 -（2 - 羟苯基）- 3,3,6,6 - 四甲基 - 1,2,3,4,5,6,7,8,9,10 - 十氢吖啶 - 1,8 - 二酮

10-(2-Hy-droxy-eth-yl)-9-(2-hy-droxy-phen-yl)-3,3,6,6-tetra-methyl-1,2,3,4,5,6,7,8,9,10-deca-hydro-acridine-1,8-dione.

作者信息

Abdelhamid Antar A, Mohamed Shaaban K, Khalilov Ali N, Gurbanov Atash V, Ng Seik Weng

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Feb 26;67(Pt 3):o744. doi: 10.1107/S1600536811006969.

DOI:10.1107/S1600536811006969
PMID:21522483
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3051986/
Abstract

The dihydro-pyridine ring in the title compound, C(25)H(31)NO(4), adopts an envelope conformation with the methine C atom representing the flap. The cyclo-hexenone rings also adopt envelope conformations with the C atoms bearing the methyl C atoms representing the flaps. The phenolic hy-droxy group forms an intra-molecular hydrogen bond to one of the two keto O atoms. The hy-droxy group of the N-bonded alkyl chain forms an inter-molecular hydrogen bond to the other keto O atom of an adjacent mol-ecule. The latter hydrogen bond leads to the formation of a helical chain running along the b axis.

摘要

标题化合物C(25)H(31)NO(4)中的二氢吡啶环呈信封式构象，次甲基C原子为折叶。环己烯酮环也呈信封式构象，带有甲基C原子的C原子为折叶。酚羟基与两个酮O原子之一形成分子内氢键。N键合烷基链的羟基与相邻分子的另一个酮O原子形成分子间氢键。后一种氢键导致沿b轴形成螺旋链。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c3/3051986/8c397c2d3140/e-67-0o744-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c3/3051986/8c397c2d3140/e-67-0o744-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c3/3051986/8c397c2d3140/e-67-0o744-fig1.jpg

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