Di Ciommo V, Ferrario F, Spina G, La Spesa F, Rubino S
Servizio di Medicina degli adolescenti, Ospedale Bambino Gesù, Palidoro, Roma.
Boll Ist Sieroter Milan. 1990 Jun;69(2):437-9.
Prevalence of HBV markers (HbsAg, anti-Hbs, anti-HBc) was retrospectively estimated in 204 adolescents (12-20 years old) of the Bambino Gesù Hospital (174 patients of orthopaedic department and 30 student nurses). HBsAg carrier rate was 3.4% (all healthy, none HBeAg positive) and prevalence of HBV marker (at least one positive) was 13.2%. Male sex, residence in the south of Italy or Italian islands, being inpatients, past surgical procedures and past hepatitis showed higher prevalences, but never significantly; anti-HBc prevalence was significantly higher in patients with a previous surgical procedure with transfusions. Future vaccinations should take into account the substantial HBV infection rate occurred as early as in adolescence.
对罗马儿童医院的204名青少年（12至20岁）（174名骨科患者和30名实习护士）进行回顾性评估，以了解乙肝病毒标志物（乙肝表面抗原、乙肝表面抗体、乙肝核心抗体）的流行情况。乙肝表面抗原携带率为3.4%（均为健康携带者，无一例乙肝e抗原阳性），乙肝病毒标志物（至少一项阳性）的流行率为13.2%。男性、居住在意大利南部或岛屿、住院患者、既往手术史和既往肝炎史的流行率较高，但均无统计学意义；既往有输血手术史的患者乙肝核心抗体流行率显著更高。未来的疫苗接种应考虑到早在青少年时期就已出现的较高乙肝病毒感染率。
