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（2E）-3-（3-溴-4-甲氧基苯基）-1-（吡啶-2-基）丙-2-烯-1-酮

(2E)-3-(3-Bromo-4-meth-oxy-phen-yl)-1-(pyridin-2-yl)prop-2-en-1-one.

作者信息

Jasinski Jerry P, Butcher Ray J, Samshuddin S, Narayana B, Yathirajan H S

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Jan 12;67(Pt 2):o352-3. doi: 10.1107/S1600536811000353.

DOI:10.1107/S1600536811000353
PMID:21523033
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3051466/
Abstract

The mean planes of the benzene and pyridine rings in the title compound, C(15)H(12)BrNO(2), are nearly coplanar, subtending an angle of 2.8 (8)°. The prop-2-en-1-one group is also in the plane of these rings with an N-C-C-O torsion angle of 179.6 (3)°. A weak C-H⋯Br inter-molecular inter-action contributes to the crystal packing, creating a chain-like structure along the a axis.

摘要

在标题化合物C(15)H(12)BrNO(2)中，苯环和吡啶环的平均平面几乎共面，夹角为2.8 (8)°。2-丙烯-1-酮基团也在这些环的平面内，N-C-C-O扭转角为179.6 (3)°。一种微弱的C-H⋯Br分子间相互作用有助于晶体堆积，沿a轴形成链状结构。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cdb/3051466/307e56a8029a/e-67-0o352-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cdb/3051466/f7a6f48a081c/e-67-0o352-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cdb/3051466/01c3ab711a62/e-67-0o352-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cdb/3051466/307e56a8029a/e-67-0o352-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cdb/3051466/f7a6f48a081c/e-67-0o352-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cdb/3051466/01c3ab711a62/e-67-0o352-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cdb/3051466/307e56a8029a/e-67-0o352-fig3.jpg

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1
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2
3,5-Bis(4-fluoro-phen-yl)-1-phenyl-4,5-dihydro-1H-pyrazole.
Acta Crystallogr Sect E Struct Rep Online. 2010 Jul 7;66(Pt 8):o1948-9. doi: 10.1107/S1600536810026036.
3
Methyl 4,6-bis-(4-fluoro-phen-yl)-2-oxo-cyclo-hex-3-ene-1-carboxyl-ate.
Acta Crystallogr Sect E Struct Rep Online. 2010 Mar 17;66(Pt 4):o864-5. doi: 10.1107/S1600536810009414.
4
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4
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6
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Acta Crystallogr Sect E Struct Rep Online. 2011 Apr 1;67(Pt 4):o756. doi: 10.1107/S160053681100701X. Epub 2011 Mar 2.
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5
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6
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7
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Bioorg Med Chem Lett. 2008 Jan 1;18(1):137-40. doi: 10.1016/j.bmcl.2007.10.114. Epub 2007 Nov 4.
8
Synthesis and antihyperglycemic activity of chalcone based aryloxypropanolamines.基于查尔酮的芳氧基丙醇胺的合成及其降血糖活性
Bioorg Med Chem. 2004 Mar 1;12(5):883-9. doi: 10.1016/j.bmc.2003.12.026.
9
Bioactivities of chalcones.查耳酮的生物活性。
Curr Med Chem. 1999 Dec;6(12):1125-49.
10
Flavonoids: old and new aspects of a class of natural therapeutic drugs.类黄酮：一类天然治疗药物的新老方面
Life Sci. 1999;65(4):337-53. doi: 10.1016/s0024-3205(99)00120-4.