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1-异丁基-N，N-二甲基-1H-咪唑并[4,5-c]喹啉-4-胺

1-Isobutyl-N,N-dimethyl-1H-imidazo[4,5-c]quinolin-4-amine.

作者信息

Loh Wan-Sin, Fun Hoong-Kun, Kayarmar Reshma, Viveka S, Nagaraja G K

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Jan 15;67(Pt 2):o405. doi: 10.1107/S160053681100153X.

DOI:10.1107/S160053681100153X
PMID:21523077
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3051498/
Abstract

In the title compound, C(16)H(20)N(4), the 1H-imidazo[4,5-c]quinoline ring system is approximately planar, with a maximum deviation of 0.0719 (15) Å. An intra-molecular C-H⋯N hydrogen bond contributes to the stabilization of the mol-ecule, forming an S(6) ring motif. In the crystal, the mol-ecules are stacked along the b axis through weak aromatic π-π inter-actions between benzene and imidazole and benzene and pyridine rings [centroid-centroid distances = 3.6055 (10) and 3.5342 (10) Å, respectively].

摘要

在标题化合物C₁₆H₂₀N₄中，1H-咪唑并[4,5-c]喹啉环系统近似平面，最大偏差为0.0719 (15) Å。分子内C-H⋯N氢键有助于分子的稳定，形成一个S(6)环模式。在晶体中，分子沿b轴堆积，通过苯环与咪唑环以及苯环与吡啶环之间的弱芳香π-π相互作用[质心-质心距离分别为3.6055 (10) 和3.5342 (10) Å]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0284/3051498/0054ed46d193/e-67-0o405-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0284/3051498/df326822bac3/e-67-0o405-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0284/3051498/0054ed46d193/e-67-0o405-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0284/3051498/df326822bac3/e-67-0o405-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0284/3051498/0054ed46d193/e-67-0o405-fig2.jpg

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