的黎波里医疗中心收治的上消化道出血成人患者的特征：一项回顾性病例系列分析。

The characteristics of adults with upper gastrointestinal bleeding admitted to Tripoli Medical Center: a retrospective case-series analysis.

机构信息

Department of Gastroenterology and Hepatology, Tripoli Medical Center, Tripoli, Libya.

出版信息

Libyan J Med. 2011 Mar 7;6. doi: 10.3402/ljm.v6i0.6283.

DOI:10.3402/ljm.v6i0.6283

PMID:21526040

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3081857/

Abstract

BACKGROUND

Acute upper gastrointestinal bleeding (UGIB) is a common reason for hospital admissions worldwide. Aetiological causes of UGIB vary according to geographic region and socioeconomic status. However, despite the implementation of early endoscopy as the standard method for the diagnosis and treatment of UGIB, data on the characteristics of patients with UGIB in Libya are still minimal. In this study, we describe patient demographics, aetiological causes for UGIB, and possible risk factors for upper gastrointestinal bleeding in patients admitted to the Gastroenterology Department at Tripoli Medical Center from January 2001 through June 2006.

METHOD

This is a retrospective case-series analysis of all adult patients with upper gastrointestinal bleeding admitted to the Gastroenterology Department at TMC. Patients' medical records were individually reviewed and relevant data abstracted.

RESULTS

A total of 928 cases with diagnoses of UGIB were admitted to Tripoli Medical Center during the study period. Of these cases, 60.3% were males and 39.7% females (3:2) and males were significantly younger than females (49.6 years vs. 53.9 years, p=0.001). The most common cause of UGIB was peptic ulcer (37.1%) of which duodenal ulcer was the most common (30.7% of all UGIB), especially amongst male patients (36.4%). The second most common cause was bleeding due to varices (29.8%), especially amongst females (35.1%). Additionally, smoking and NSAIDs use were reported by 18.6% and 9.7% of cases and both were significantly associated with bleeding due to peptic ulcers.

CONCLUSION

This study has investigated the characteristics of adults with UGIB at a tertiary referral center in Libya. The high frequency of bleeding due to varices amongst females mandates further investigations into the possible underlying hepatic causes and their management, and the potential impact on patient outcome and prognosis.

摘要

背景

急性上消化道出血（UGIB）是全球范围内医院收治的常见原因。UGIB 的病因因地理位置和社会经济地位而异。然而，尽管早期内镜检查已被作为诊断和治疗 UGIB 的标准方法实施，但有关利比亚 UGIB 患者特征的数据仍很少。在本研究中，我们描述了 2001 年 1 月至 2006 年 6 月期间入住的黎波里医疗中心消化科的患者人口统计学、UGIB 的病因以及上消化道出血的可能危险因素。

方法

这是对 TMC 消化科收治的所有上消化道出血成年患者的回顾性病例系列分析。单独审查了患者的病历并提取了相关数据。

结果

在研究期间，共有 928 例 UGIB 患者入住的黎波里医疗中心。其中 60.3%为男性，39.7%为女性（3:2），男性明显比女性年轻（49.6 岁对 53.9 岁，p=0.001）。UGIB 的最常见病因是消化性溃疡（37.1%），其中十二指肠溃疡最为常见（占所有 UGIB 的 30.7%），尤其是男性患者（36.4%）。其次是静脉曲张出血（29.8%），尤其是女性（35.1%）。此外，18.6%和 9.7%的病例报告了吸烟和 NSAIDs 使用，且两者均与消化性溃疡出血明显相关。