拉丁美洲移民孕妇的恰加斯病：非流行国家的经验。
Chagas disease in Latin American pregnant immigrants: experience in a non-endemic country.
机构信息
Infectious Diseases Unit, Hospital General Universitario de Elche, Elche, Spain.
出版信息
Arch Gynecol Obstet. 2012 Apr;285(4):919-23. doi: 10.1007/s00404-011-2081-9. Epub 2011 Sep 17.
PURPOSE
Chagas disease is a systemic chronic parasitic infection by Trypanosoma cruzi endemic in Latin America. Migration of women of childbearing age from Latin America to developed countries may spread the disease to non-endemic areas through vertical transmission.
METHODS
Prospective study of seroprevalence of T. cruzi infection in immigrant Latin American pregnant women during a 5-year period (from 2006 to 2010) in Spain.
RESULTS
Seven out of 545 participants were seropositive for T. cruzi [prevalence 1.28%, 95% confidence interval (CI) 0.06-2.56]. Four (57%) were from Bolivia and three (43.%) from Paraguay. The seroprevalence in pregnant women from Bolivia was 10.26% (95% CI 4.06-23.58) and in participants from Paraguay was 6.52% (95% CI 2.24-17.5). No congenital transmission occurred.
CONCLUSIONS
Seroprevalence of T. cruzi infection in Latin American pregnant women coming from Bolivia and Paraguay is high. Those women should be screened for T. cruzi to control mother-to-child transmission in non-endemic areas.
目的
恰加斯病是一种由克氏锥虫引起的系统性慢性寄生虫感染，流行于拉丁美洲。生育年龄的妇女从拉丁美洲移民到发达国家，可能通过垂直传播将该病传播到非流行地区。
方法
对西班牙 5 年来（2006 年至 2010 年）拉丁美洲移民孕妇中克氏锥虫感染的血清流行率进行前瞻性研究。
结果
545 名参与者中有 7 人（1.28%，95%置信区间 0.06-2.56）血清呈克氏锥虫阳性。其中 4 人（57%）来自玻利维亚，3 人（43%）来自巴拉圭。来自玻利维亚的孕妇血清阳性率为 10.26%（95%置信区间 4.06-23.58），来自巴拉圭的孕妇血清阳性率为 6.52%（95%置信区间 2.24-17.5）。未发生先天性传播。
结论
来自玻利维亚和巴拉圭的拉丁美洲孕妇克氏锥虫感染的血清流行率较高。这些妇女应接受克氏锥虫筛查，以控制非流行地区的母婴传播。
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