Herwig M C, Hubbard G B, Wells J R, Grossniklaus H E
Emory Eye Center, L.F. Montgomery Laboratory, Emory University, BT 428, 1365 Clifton Road NE, Atlanta, Georgia 30322, USA.
Ophthalmologe. 2011 Oct;108(10):969-72. doi: 10.1007/s00347-011-2369-y.
Retinoblastoma is the most common primary intraocular tumor in childhood. Diffuse anterior retinoblastoma is an uncommon variant and usually occurs in comparatively older children. Typically, there is an extensive infiltration of the anterior segment by tumor cells clinically mimicking anterior uveitis with pseudohypopyon. The actual retinal focus is often very small and may not be detected despite a thorough histological examination. In this case report the clinical and histological findings of a diffuse anterior retinoblastoma are described.
视网膜母细胞瘤是儿童期最常见的原发性眼内肿瘤。弥漫性前部视网膜母细胞瘤是一种罕见的变异型，通常发生在年龄稍大的儿童中。典型情况下，肿瘤细胞广泛浸润眼前节，临床上表现为类似伴有假前房积脓的前葡萄膜炎。实际的视网膜病灶往往非常小，即使经过全面的组织学检查也可能无法检测到。在本病例报告中，描述了一例弥漫性前部视网膜母细胞瘤的临床和组织学表现。
