Grossniklaus H E, Dhaliwal R S, Martin D F
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA.
Retina. 1998;18(3):238-41. doi: 10.1097/00006982-199803000-00008.
The authors describe the clinicopathologic features of an anterior variant of diffuse retinoblastoma.
The clinical history of a child with an anterior chamber infiltrate and cells in the anterior vitreous was reviewed. An anterior chamber aspirate was processed by a Millipore filter technique. The eye was enucleated and routinely processed for light and transmission electron microscopic examination.
An 8-year-old girl was treated for anterior uveitis in her right eye that failed to resolve. Examination of an anterior chamber aspirate showed cells suggestive of retinoblastoma. The eye was enucleated, and the enucleation specimen showed retinoblastoma confined to the iris, ciliary body, and anterior vitreous with one microscopic focus of tumor in the peripheral retina.
This variant of diffuse retinoblastoma involved only anterior ocular structures with minimal involvement of the retina.
作者描述弥漫性视网膜母细胞瘤前房变异型的临床病理特征。
回顾一名患有前房浸润及前玻璃体细胞的儿童的临床病史。前房穿刺液采用密理博滤膜技术处理。眼球被摘除并常规进行光镜和透射电镜检查。
一名8岁女孩因右眼前葡萄膜炎治疗无效前来就诊。前房穿刺液检查发现提示视网膜母细胞瘤的细胞。眼球被摘除，摘除标本显示视网膜母细胞瘤局限于虹膜、睫状体和前玻璃体，周边视网膜有一个微小肿瘤病灶。
这种弥漫性视网膜母细胞瘤变异型仅累及眼前部结构，视网膜受累极少。
