Steinberg H V, Alarcon J J, Bernardino M E
Department of Radiology, Emory University School of Medicine, Atlanta, GA 30322.
Radiology. 1990 Jan;174(1):153-6. doi: 10.1148/radiology.174.1.2152980.
Twenty-nine patients with known or suspected malignancy were studied with identical T1-weighted (spin echo [SE] and inversion recovery [IR]) and T2-weighted SE magnetic resonance (MR) imaging at 0.5 and 1.5 T to evaluate the relative sensitivities of these sequences for detecting focal hepatic lesions. At 0.5 T, 98 lesions were detected with the IR sequence, 86 with the T1-weighted SE sequence, and 96 with the T2-weighted sequence. At 1.5 T, 93 lesions were detected with the IR sequence, 70 with the T1-weighted SE sequence, and 99 with the T2-weighted sequence. Although the lack of pathologic correlation precluded establishment of true sensitivity and specificity rates, data showed that magnetic field strength resulted in no significant difference for detecting focal hepatic lesions. No single sequence was shown to be significantly superior, although the T1-weighted SE sequence at 1.5 T was significantly inferior to the other sequences for detecting focal hepatic lesions. T1-weighted SE imaging at 0.5 T was significantly inferior to T1-weighted IR and T2-weighted imaging at both magnetic field strengths for detecting focal lesions in the left lobe of the liver. The authors conclude that T1-weighted IR and T2-weighted sequences alone will result in optimal MR imaging for the detection of focal hepatic lesions at 0.5 and 1.5 T.
对29例已知或疑似患有恶性肿瘤的患者,采用相同的T1加权(自旋回波[SE]和反转恢复[IR])以及T2加权SE磁共振(MR)成像,分别在0.5T和1.5T磁场强度下进行检查,以评估这些序列检测肝脏局灶性病变的相对敏感性。在0.5T时,IR序列检测到98个病变,T1加权SE序列检测到86个病变,T2加权序列检测到96个病变。在1.5T时,IR序列检测到93个病变,T1加权SE序列检测到70个病变,T2加权序列检测到99个病变。尽管缺乏病理对照,无法确定真正的敏感性和特异性,但数据显示磁场强度对检测肝脏局灶性病变无显著差异。没有单一序列显示出明显优势,尽管1.5T时的T1加权SE序列在检测肝脏局灶性病变方面明显逊于其他序列。在检测肝脏左叶局灶性病变时,0.5T时的T1加权SE成像在两种磁场强度下均明显逊于T1加权IR成像和T2加权成像。作者得出结论,单独使用T1加权IR和T2加权序列将能在0.5T和1.5T时实现检测肝脏局灶性病变的最佳MR成像。