Baylor College of Medicine, Houston, Texas, USA.
J Arthroplasty. 2011 Dec;26(8):1251-8.e1-4. doi: 10.1016/j.arth.2011.02.029. Epub 2011 Apr 29.
Four wound closure techniques for total knee arthroplasty were compared in a prospective, randomized, controlled, institutional review board-approved study with 75 subjects. The study compared tissue adhesives, stapling, and suturing with respect to procedure time and cost, together with functional and clinical outcome. Total knee arthroplasty closure time (capsule to cutaneous) favored staples at 26 s/cm, followed by adhesives (45 and 37 s/cm for 2-octyl and n-butyl-2, respectively) and, finally, subcuticular suturing at 54 s/cm (P < .0007). Reduced procedure time translated into intraoperative cost reduction where closure cost per centimeter was $70, $62, $57, and $75 for 2-octyl, n-butyl-2, staples, and sutures, respectively. No significant differences in infection, dehiscence, cosmesis, general health (SF-12v2 (QualityMetric Inc., Lincoln, RI)), and functional and clinical assessments (range of motion, Knee Society knee score, and pain) were observed.
在一项前瞻性、随机、对照、机构审查委员会批准的研究中，对 75 名受试者进行了 4 种全膝关节置换术的伤口闭合技术比较。该研究比较了组织粘合剂、缝合钉和缝线在手术时间和成本方面的差异，同时还比较了功能和临床结果。全膝关节置换术的闭合时间（从关节囊到皮肤）以缝合钉为优，用时 26 秒/厘米，其次是粘合剂（2-辛基和正丁基-2 分别为 45 和 37 秒/厘米），最后是皮下缝线，用时 54 秒/厘米（P<0.0007）。手术时间的缩短转化为术中成本的降低，每厘米的闭合成本分别为 2-辛基、正丁基-2、缝合钉和缝线的 70 美元、62 美元、57 美元和 75 美元。在感染、裂开、美容效果、一般健康状况（SF-12v2（QualityMetric Inc.，Lincoln，RI））和功能及临床评估（活动范围、膝关节协会膝关节评分和疼痛）方面均未观察到显著差异。
