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在“组学”时代的真菌致病性基因。

Fungal pathogenicity genes in the age of 'omics'.

机构信息

School of Botany, University of Melbourne, Vic. 3010, Australia.

出版信息

Mol Plant Pathol. 2011 Jun;12(5):507-14. doi: 10.1111/j.1364-3703.2010.00680.x. Epub 2010 Dec 6.

DOI:10.1111/j.1364-3703.2010.00680.x
PMID:21535355
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6640419/
Abstract

The identification of the fungal genes essential for disease underpins the development of disease control strategies. Improved technologies for gene identification and functional analyses, as well as a plethora of sequenced fungal genomes, have led to the characterization of hundreds of genes, denoted as pathogenicity genes, which are required by fungi to cause disease. We describe recent technologies applied to characterize the fungal genes involved in disease and focus on some genes that are likely to attract continuing research activity.

摘要

鉴定对疾病至关重要的真菌基因是制定疾病控制策略的基础。基因鉴定和功能分析技术的改进,以及大量测序的真菌基因组,已经导致了数百个基因的特征描述,这些基因被称为致病性基因,是真菌引起疾病所必需的。我们描述了最近应用于鉴定与疾病有关的真菌基因的技术,并重点介绍了一些可能吸引持续研究活动的基因。

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本文引用的文献

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Science. 2010 Aug 20;329(5994):953-5. doi: 10.1126/science.1190859.
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New developments in pathogenicity and virulence of necrotrophs.坏死营养型病原菌的致病性和毒力的新进展。
Curr Opin Plant Biol. 2010 Aug;13(4):415-9.
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The use of FLP-mediated recombination for the functional analysis of an effector gene family in the biotrophic smut fungus Ustilago maydis.利用 FLP 介导的重组技术对生物寄生性黑粉菌玉米黑粉菌中的一个效应基因家族进行功能分析。
New Phytol. 2010 Sep;187(4):957-968. doi: 10.1111/j.1469-8137.2010.03413.x. Epub 2010 Jun 18.
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Host-selective toxins, Ptr ToxA and Ptr ToxB, as necrotrophic effectors in the Pyrenophora tritici-repentis-wheat interaction.寄主选择性毒素 Ptr ToxA 和 Ptr ToxB 作为禾谷丝核菌-小麦互作中的坏死型效应因子。
New Phytol. 2010 Sep;187(4):911-9. doi: 10.1111/j.1469-8137.2010.03362.x. Epub 2010 Jul 14.
5
The autophagy genes ATG8 and ATG1 affect morphogenesis and pathogenicity in Ustilago maydis.自噬基因 ATG8 和 ATG1 影响玉米黑粉菌的形态发生和致病性。
Mol Plant Pathol. 2010 Jul;11(4):463-78. doi: 10.1111/j.1364-3703.2010.00620.x.
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Pathogenesis, parasitism and mutualism in the trophic space of microbe-plant interactions.微生物-植物相互作用的营养空间中的发病机制、寄生和共生。
Trends Microbiol. 2010 Aug;18(8):365-73. doi: 10.1016/j.tim.2010.06.002. Epub 2010 Jul 1.
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