Lund Helle, Kofoed Steen Christian, Hillingsø Jens Georg, Falck-Larsen Claus, Svendsen Lars Bo
Department of Surgery and Trauma Unit, Rigshospitalet, 2100 Copenhagen Ø, Denmark.
Dan Med Bull. 2011 May;58(5):A4275.
Hypovolaemic shock is a major course of death in trauma patients. The mortality in patients in profound shock at the time of arrival is extremely high and we wanted to investigate the outcome of patients undergoing laparotomy at the Trauma Care Unit (TCU).
Forty-four emergency laparotomies performed at the TCU at Rigshospitalet between January 2003 and December 2009 were registered. The indication for surgical intervention was based on persisting, unstable haemodynamics and either positive findings at focused abdominal sonography in trauma (FAST) or penetrating injury. In some patients, laparotomy was performed despite a negative FAST because of ongoing instability. The patients were stratified according to their systolic blood pressure (BP).
After 24 hours, 46% (20 patients) of the patients were alive. The survival after 30 days was 41% (18 patients). Stratifying the patients into three categories according to the systolic BP at the time of arrival (BP > 80 mmHg (n = 14), 80 mmHg ≥ BP > 60 mmHg (n = 10) and BP ≤ 60 mmHg (n = 20) revealed a 64%, 50% and 34% survival rate within the first 24 hours (p = 0.04). In the group of patients with BP ≤ 60 mmHg, the survival decreased to 20% after 30 days. Stratification by penetrating or blunt trauma showed no significant difference in survival (40% versus 50% survival after 30 days) (p = 0.40). However, in those patients arriving with BP ≤ 60 mmHg (five penetrating and 15 blunt injuries), we found that the survival rate after laparotomy was 60% and 13%, respectively.
The present study shows that haemodynamically unstable patients with abdominal or suspected abdominal injuries undergoing emergency laparotomy have a high mortality, especially those with BP ≤ 60 mmHg. Patients with a penetrating trauma have a far better prognosis than those with a blunt trauma.
低血容量性休克是创伤患者死亡的主要原因。到达时处于深度休克状态的患者死亡率极高,我们想要研究在创伤护理单元(TCU)接受剖腹手术患者的预后情况。
记录了2003年1月至2009年12月期间在里格霍斯医院TCU进行的44例急诊剖腹手术。手术干预的指征基于持续的、不稳定的血流动力学状态以及创伤重点腹部超声检查(FAST)阳性结果或穿透伤。在一些患者中,尽管FAST结果为阴性,但由于血流动力学持续不稳定仍进行了剖腹手术。根据患者的收缩压(BP)进行分层。
24小时后,46%(20例患者)存活。30天后的生存率为41%(18例患者)。根据到达时的收缩压将患者分为三类(收缩压>80 mmHg(n = 14)、80 mmHg≥收缩压>60 mmHg(n = 10)和收缩压≤60 mmHg(n = 20)),结果显示在最初24小时内的生存率分别为64%、50%和34%(p = 0.04)。在收缩压≤60 mmHg的患者组中,30天后生存率降至20%。按穿透伤或钝性伤分层显示生存率无显著差异(30天后生存率分别为40%和50%)(p = 0.40)。然而,在那些到达时收缩压≤60 mmHg的患者中(5例穿透伤和15例钝性伤),我们发现剖腹手术后的生存率分别为60%和13%。
本研究表明,因腹部或疑似腹部损伤而接受急诊剖腹手术的血流动力学不稳定患者死亡率很高,尤其是那些收缩压≤60 mmHg的患者。穿透伤患者的预后远优于钝性伤患者。