Suppr超能文献

穿透性腹部创伤后血流动力学“稳定”的腹膜炎患者:识别那些正在出血的患者。

Hemodynamically "stable" patients with peritonitis after penetrating abdominal trauma: identifying those who are bleeding.

作者信息

Brown Carlos V R, Velmahos George C, Neville Angela L, Rhee Peter, Salim Ali, Sangthong Burapat, Demetriades Demetrios

机构信息

Department of Surgery, Division of Trauma and Critical Care, University of Southern California Keck School of Medicine, Los Angeles County/University of Southern California Medical Center, 1200 N. State Street, Los Angeles, CA 90033, USA.

出版信息

Arch Surg. 2005 Aug;140(8):767-72. doi: 10.1001/archsurg.140.8.767.

Abstract

HYPOTHESIS

Despite initial presentation, hemodynamically stable patients with penetrating abdominal trauma may have significant ongoing hemorrhage and major intra-abdominal injuries requiring emergent surgical intervention.

DESIGN

Cohort analytic study.

SETTING

Academic, level I trauma center.

PATIENTS

One hundred thirty-nine consecutive hemodynamically stable patients with penetrating abdominal trauma in whom peritonitis was the sole indication for laparotomy.

MAIN OUTCOME MEASURES

The primary outcome was the amount of blood initially found at laparotomy. Secondary outcomes included additional intraoperative blood loss, intraoperative hypotension, transfusion, fluid, and vasopressor requirement; need for admission to the intensive care unit and mechanical ventilation; complications; survivor length of stay in the hospital and intensive care unit; and mortality.

RESULTS

The admission systolic blood pressure (mean +/- SD, 131 +/- 22 mm Hg) and heart rate (mean +/- SD, 91 +/- 22 beats/min) were normal. Median time from peritonitis to incision was 40 minutes. Ninety-seven percent of patients had intra-abdominal injury, including 81%, hollow visceral; 36%, solid organ; and 11%, vascular injury. Though most patients had less than 750 mL(3) of blood found initially at laparotomy, there were 11% with 750 to 1500 mL(3) and 7% with 1500 mL(3) or more. Intraoperative hypotension (25%) and blood transfusion (39%) were common. Postoperatively, 40% of patients required intensive care (78% of them requiring mechanical ventilation) and 19% required additional transfusion within 24 hours. Complications occurred in 25% of patients, with intra-abdominal abscess (12%) and wound infection (7%) being the most common. Three patients died, 2 of exsanguination and 1 of multisystem organ failure.

CONCLUSIONS

Following penetrating abdominal trauma, peritonitis should be a trigger for emergent operation regardless of vital signs, because hemodynamic "stability" does not reliably exclude significant hemorrhage. Vascular injury, subsequent hypotension, blood transfusion, and complicated postoperative course are common in this population.

摘要

假设

尽管初始表现正常,但腹部穿透伤后血流动力学稳定的患者可能存在持续的大量出血和严重的腹腔内损伤,需要紧急手术干预。

设计

队列分析研究。

地点

一级学术创伤中心。

患者

139例连续的腹部穿透伤后血流动力学稳定的患者,其中腹膜炎是剖腹手术的唯一指征。

主要观察指标

主要观察指标是剖腹手术时最初发现的出血量。次要观察指标包括术中额外失血量、术中低血压、输血、补液和血管升压药的使用情况;入住重症监护病房和机械通气的需求;并发症;幸存者在医院和重症监护病房的住院时间;以及死亡率。

结果

入院时收缩压(均值±标准差,131±22 mmHg)和心率(均值±标准差,91±22次/分钟)正常。从腹膜炎到手术切开的中位时间为40分钟。97%的患者存在腹腔内损伤,包括81%的中空脏器损伤、36%的实体脏器损伤和11%的血管损伤。虽然大多数患者在剖腹手术时最初发现的出血量少于750 mL,但有11%的患者出血量在750至1500 mL之间,7%的患者出血量在1500 mL或更多。术中低血压(25%)和输血(39%)很常见。术后,40%的患者需要重症监护(其中78%需要机械通气),19%的患者在24小时内需要额外输血。25%的患者发生并发症,腹腔内脓肿(12%)和伤口感染(7%)最为常见。3例患者死亡,2例死于失血,1例死于多系统器官衰竭。

结论

腹部穿透伤后,无论生命体征如何,腹膜炎都应作为紧急手术的触发因素,因为血流动力学“稳定”并不能可靠地排除严重出血。该人群中血管损伤、随后的低血压、输血和术后复杂病程很常见。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验