Castella-Escola J, Mattei M G, Ojcius D M, Passage E, Valentin C, Cohen-Solal M
Unité INSERM U91, Hôpital Henri Mondor, Créteil, France.
Hum Genet. 1990 Jan;84(2):210-2. doi: 10.1007/BF00208945.
A 2.3-kb-long probe derived from the 5' flanking region, the first exon and part of the first intron of the human muscle-specific phosphoglycerate mutase gene (PGAM-M) (EC 5.4.2.1) was used to map the gene by "in situ" chromosomal hybridization. The structural gene for PGAM-M was assigned to chromosome 7p12-7p13; a single hybridization peak indicated that there is a single gene for this isozyme of PGAM, and confirmed results obtained by Southern blot hybridization.
从人肌肉特异性磷酸甘油酸变位酶基因(PGAM-M)(EC 5.4.2.1)的5'侧翼区、第一个外显子和第一个内含子的一部分获得的一个2.3千碱基长的探针,用于通过“原位”染色体杂交对该基因进行定位。PGAM-M的结构基因被定位于染色体7p12 - 7p13;单个杂交峰表明该PGAM同工酶存在单个基因,并证实了通过Southern印迹杂交获得的结果。