Mrabti H, El Ghissassi I, Sbitti Y, Amrani M, Hachi H, Errihani H
Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.
Case Rep Med. 2011;2011:123527. doi: 10.1155/2011/123527. Epub 2011 Apr 7.
The growing teratoma syndrome (GTS) is defined as a detection of an enlarged mass during or after chemotherapy treatment for germ cell tumor. We report a case of an 18-year-old girl treated for growing teratoma syndrome after chemotherapy for malignant germ cell tumor of the ovary associated with peritoneal gliomatosis. Chemotherapy induced normalisation of alpha-fetoprotein rate whereas there was an enlargement of the mass. Subsequent complete resection was performed, and the patient remained in good control for 60 months. This clinical picture suggested the diagnosis of "GTS". This syndrome can lead to confusion with progression or relapse of a germ cell tumour because of increase in tumour volume during chemotherapy, so it is important to recognize it.
生长性畸胎瘤综合征（GTS）定义为在生殖细胞肿瘤化疗期间或化疗后检测到肿块增大。我们报告一例18岁女孩，其因卵巢恶性生殖细胞肿瘤伴腹膜胶质瘤病接受化疗后发生生长性畸胎瘤综合征。化疗使甲胎蛋白率恢复正常，但肿块却增大。随后进行了完整切除，患者在60个月内病情控制良好。此临床情况提示“GTS”的诊断。由于化疗期间肿瘤体积增大，该综合征可能导致与生殖细胞肿瘤进展或复发相混淆，因此识别它很重要。
