Silva Vanessa Giendruczak da, Amaral Carolina, Monteiro Mariane Borba, Nascimento Daniela Meirelles do, Boschetti Jaqueline Regina
Irmandade da Santa Casa de Misericordia de Porto Alegre, Brasil.
J Bras Nefrol. 2011 Mar;33(1):62-8.
Chronic kidney disease associated with hemodialysis can have a variety of musculoskeletal complications, in addition to repercussions in pulmonary function.
To evaluate the effects of inspiratory muscle training on inspiratory muscle strength, pulmonary function, and functional capacity in patients with chronic kidney failure undergoing hemodialysis.
Non-controlled clinical trial, comprising 15 individuals diagnosed with chronic kidney failure and undergoing hemodialysis. Maximum inspiratory (PImax) and expiratory (PEmax) pressures were assessed by use of pressure vacuum meter reading. Pulmonary function was assessed by use of spirometry. Functional capacity was assessed by use of walked distance and oxygen consumption obtained in the six-minute walk test (6MWT). For eight weeks, the inspiratory muscle training (IMT) protocol was applied during hemodialysis sessions, with load set to 40% of PImax and weekly frequency of three alternate days.
A significant increase in the walked distance was observed after training (455.5 ± 98 versus 557.8 ± 121.0; p = 0.003). No statistically significant difference was observed in the other variables when comparing their pre- and posttraining values.
The study showed no statistically significant difference in respiratory muscle strength, pulmonary function, and oxygen consumption. An increase in the walked distance was observed in the 6MWT.
与血液透析相关的慢性肾病除了会对肺功能产生影响外，还会引发多种肌肉骨骼并发症。
评估吸气肌训练对接受血液透析的慢性肾衰竭患者吸气肌力量、肺功能和功能能力的影响。
非对照临床试验，纳入15名被诊断为慢性肾衰竭并接受血液透析的个体。使用压力真空计读数评估最大吸气压力（PImax）和最大呼气压力（PEmax）。使用肺活量测定法评估肺功能。使用六分钟步行试验（6MWT）中的步行距离和耗氧量评估功能能力。在血液透析期间应用吸气肌训练（IMT）方案，为期八周，负荷设定为PImax的40%，每周频率为隔天进行三次。
训练后观察到步行距离显著增加（455.5±98对557.8±121.0；p = 0.003）。比较训练前后的值时，其他变量未观察到统计学上的显著差异。
该研究表明，呼吸肌力量、肺功能和耗氧量在统计学上无显著差异。在6MWT中观察到步行距离增加。
