UNIV TEXAS,HLTH SCI CTR,DEPT MED,DIV ENDOCRINOL & METAB,SAN ANTONIO,TX 78284.
Int J Oncol. 1996 Jul;9(1):103-9. doi: 10.3892/ijo.9.1.103.
Breast cancer frequently and preferentially spreads to bone. Once breast cancer colonizes bone, it is essentially incurable. The cellular and molecular mechanisms by which breast cancer selectively metastasizes to bone remain largely unknown. Elucidation of these mechanisms should lead to the development of effective and specific therapeutic strategies for bone metastasis of breast cancer.
乳腺癌经常且优先转移到骨骼。一旦乳腺癌在骨骼中定植，它基本上就是不可治愈的。乳腺癌选择性转移到骨骼的细胞和分子机制在很大程度上仍然未知。阐明这些机制应该会为乳腺癌骨转移的治疗策略的发展提供有效的、有针对性的方法。
