Shamova E V, Bichan O D, Drozd E S, Gorudko I V, Chizhik S A, Shumaev K B, Cherenkevich S N, Vanin A F
Biofizika. 2011 Mar-Apr;56(2):265-71.
The effect of NO donors (sodium nitroprusside, S-nitrosoglutathione, dinitrosyl-iron complexes) on the functional and mechanical properties of human platelets and red blood cells has been investigated. It has been established by atomic force microscopy that NO donor-induced platelet disaggregation is accompanied by changes in the elastic properties of cells. It has been shown that, in the presence of NO donors, the detergent-induced hemolysis of red blood cells is delayed, and the elasticity modulus of these cells decreases. The results obtained indicate that NO donors regulate the structural and functional properties of platelets and red blood cells.
已研究了一氧化氮供体（硝普钠、S-亚硝基谷胱甘肽、二亚硝基铁配合物）对人血小板和红细胞功能及力学性能的影响。通过原子力显微镜已证实，一氧化氮供体诱导的血小板解聚伴随着细胞弹性特性的变化。结果表明，在一氧化氮供体存在的情况下，去污剂诱导的红细胞溶血延迟，且这些细胞的弹性模量降低。所得结果表明，一氧化氮供体可调节血小板和红细胞的结构及功能特性。
