Center for Sports Medicine, University Medical Center Groningen, The Netherlands.
Br J Sports Med. 2011 Oct;45(13):1068-76. doi: 10.1136/bjsm.2010.078824. Epub 2011 May 3.
Injection treatments are increasingly used as treatment for patellar tendinopathy. The aim of this systematic review is to describe the different injection treatments, their rationales and the effectiveness of treating patellar tendinopathy.
A computerised search of the Medline, Embase, CINAHL and Web of Knowledge databases was conducted on 1 May 2010 to identify studies on injection treatments for patellar tendinopathy.
11 articles on seven different injection treatments (dry needling, autologous blood, high-volume, platelet-rich plasma, sclerosis, steroids and aprotinin injections) were found: 4 randomised controlled trials (RCTs), 1 non-RCT, 4 prospective cohort studies and 2 retrospective cohort studies. All studies reported positive results. The Delphi scores of the four RCTs ranged from 5 to 8 out of 9. Different and sometimes contradictory rationales were used for the injection treatments.
All seven different injection treatments seem promising for treating patellar tendinopathy. Unlike the other injection treatments, steroid treatment often shows a relapse of symptoms in the long term. Results should be interpreted with caution as the number of studies is low, few high-quality studies have been conducted and the studies are hard to compare due to different methodology. More high-quality studies using the same cross-cultural reliable and valid outcome measure are needed, as well as further research into the pathophysiology. Finally, some implications are provided for clinicians who want to use injection treatments as a part of their treatment for patellar tendinopathy, distinguishing between reactive and degenerative phase of patellar tendinopathy.
注射治疗越来越多地被用于治疗髌腱病。本系统综述旨在描述不同的注射治疗方法、其原理以及治疗髌腱病的效果。
2010 年 5 月 1 日,我们对 Medline、Embase、CINAHL 和 Web of Knowledge 数据库进行了计算机检索,以确定有关髌腱病注射治疗的研究。
共发现 11 篇关于 7 种不同注射治疗方法(干针、自体血、高容量、富含血小板的血浆、硬化、皮质类固醇和抑肽酶注射)的文章:4 项随机对照试验(RCT)、1 项非 RCT、4 项前瞻性队列研究和 2 项回顾性队列研究。所有研究均报告了阳性结果。4 项 RCT 的 Delphi 评分范围为 9 分中的 5-8 分。不同的、有时甚至是相互矛盾的原理被用于这些注射治疗。
这 7 种不同的注射治疗方法似乎都有希望治疗髌腱病。与其他注射治疗不同,皮质类固醇治疗在长期往往会导致症状复发。由于研究数量较少,进行的高质量研究较少,而且由于研究方法不同,难以进行比较,因此结果应谨慎解释。需要更多的高质量研究,使用相同的跨文化可靠和有效的结果测量方法,并进一步研究病理生理学。最后,为希望将注射治疗作为髌腱病治疗一部分的临床医生提供了一些建议,区分髌腱病的反应期和退行期。