Departamento de Bioquímica, Biología Celular y Molecular de Plantas, Estación Experimental del Zaidín (EEZ), CSIC, Granada, Spain.
Plant Signal Behav. 2011 Jun;6(6):789-93. doi: 10.4161/psb.6.6.15161. Epub 2011 Jun 1.
During the last decade, it was established that the class III alcohol dehydrogenase (ADH3) enzyme, also known as glutathione-dependent formaldehyde dehydrogenase (FALDH; EC 1.2.1.1), catalyzes the NADH-dependent reduction of S-nitrosoglutathione (GSNO) and therefore was also designated as GSNO reductase. This finding has opened new aspects in the metabolism of nitric oxide (NO) and NO-derived molecules where GSNO is a key component. In this article, current knowledge of the involvement and potential function of this enzyme during plant development and under biotic/abiotic stress is briefly reviewed.
在过去的十年中,已经确定 III 类醇脱氢酶(ADH3),也称为谷胱甘肽依赖型甲醛脱氢酶(FALDH;EC 1.2.1.1),能够催化 NADH 依赖型 S-亚硝酰谷胱甘肽(GSNO)的还原,因此也被指定为 GSNO 还原酶。这一发现为一氧化氮(NO)和 NO 衍生分子的代谢开辟了新的方面,GSNO 是其中的关键组成部分。本文简要综述了该酶在植物发育过程中以及在生物/非生物胁迫下的参与和潜在功能的现有知识。