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通过 56 天的饮食暴露,研究了鲤鱼(Perca fluviatilis)肌肉组织中的多环芳烃和羟基代谢物。

Polycyclic aromatic hydrocarbons and hydroxylated metabolites in the muscle tissue of Eurasian perch (Perca fluviatilis) through dietary exposure during a 56-day period.

机构信息

Nancy Université, INRA, UR AFPA, 2 Avenue de la Forêt de Haye, B.P. 172, F-54505 Vandœuvre-lès-Nancy cedex, France.

出版信息

Chemosphere. 2011 Sep;84(10):1489-94. doi: 10.1016/j.chemosphere.2011.04.037. Epub 2011 May 5.

DOI:10.1016/j.chemosphere.2011.04.037
PMID:21546054
Abstract

Eurasian perch (Perca fluviatilis) was exposed trophically to phenanthrene, pyrene and benzo[a]pyrene. Accumulation kinetics in the muscle tissue of parent PAHs and hydroxylated metabolites were established for 56 days at 3 levels of exposure (0, 100 and 500 μg/kg BW). Benzo[a]pyrene and 3-hydroxy-benzo[a]pyrene were not detected in the muscles. During exposure, there was an increase in phenanthrene, pyrene and their hydroxylated metabolites in the muscle tissue. Low transfer to muscle tissue was observed at equilibrium for phenanthrene (4.4±0.6% and 2.7±0.8%) and pyrene (1.0±0.2% and 0.33±0.09%), depending on the concentrations in the spiked feed.

摘要

欧鳊(Perca fluviatilis)通过摄食暴露于菲、芘和苯并[a]芘中。在 3 个暴露水平(0、100 和 500 μg/kg BW)下,56 天内建立了亲代多环芳烃及其羟基代谢物在肌肉组织中的积累动力学。肌肉中未检测到苯并[a]芘和 3-羟基苯并[a]芘。在暴露期间,肌肉组织中菲、芘及其羟基代谢物的含量增加。在平衡时,低浓度的菲(4.4±0.6%和 2.7±0.8%)和芘(1.0±0.2%和 0.33±0.09%)转移到肌肉组织中,这取决于添加饲料中的浓度。

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