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晚期乳腺癌的肿瘤特异性全身治疗——持续多久才合理?

Tumor-Specific Systemic Treatment in Advanced Breast Cancer - How Long does it Make Sense?

作者信息

Wuerstlein Rachel, Bauerfeind Ingo

机构信息

Brustzentrum, Universitäts-Frauenklinik, Universitätsklinikum Köln, Germany.

出版信息

Breast Care (Basel). 2011;6(1):35-41. doi: 10.1159/000324455. Epub 2011 Feb 15.

Abstract

SUMMARY

Metastatic breast cancer (MBC) is a chronic and incurable disease which can be kept steady for a long time with continuous oncologic therapy. There are various treatment options. Disease-free as well as overall survival were prolonged in many pharmaceutical studies. The therapist focuses on these oncologic parameters as well as the patient's quality of life. One central point of the communication between doctor and patient is the prediction by the medical team of how long to continue oncologic therapy and when to start palliative medicine in terms of best palliative care. Treatment options currently available for MBC as well as the importance of this difficult communication between the involved parties are pointed out. The end of tumor-specific oncologic therapy does not necessarily mean the end of therapeutic measures for the individual patient.

摘要

摘要

转移性乳腺癌(MBC)是一种慢性不治之症,通过持续的肿瘤治疗可长期保持稳定。有多种治疗选择。在许多药物研究中,无病生存期和总生存期都得到了延长。治疗师关注这些肿瘤学参数以及患者的生活质量。医患沟通的一个核心要点是医疗团队对肿瘤治疗持续时间的预测,以及就最佳姑息治疗而言何时开始使用姑息药物。指出了目前MBC可用的治疗选择以及相关各方之间这种艰难沟通的重要性。肿瘤特异性肿瘤治疗的结束并不一定意味着个体患者治疗措施的结束。

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