Delacourt C
Service de pneumologie pédiatrique, hôpital Necker-Enfants-Malades, 161, rue de Sèvres, 75015 Paris, France.
Rev Mal Respir. 2011 Apr;28(4):529-41. doi: 10.1016/j.rmr.2010.10.038. Epub 2011 Apr 1.
Primary infection with Mycobacterium tuberculosis usually occurs during childhood. The source of infection is most often an adult. The risk of infection in exposed children is modulated by various factors related to the infectiousness of the index case, exposure conditions, and the child himself. This review aims to describe the specific diagnostic and therapeutic features of latent TB infection and TB disease in childhood.
结核分枝杆菌的原发性感染通常发生在儿童期。感染源最常见的是成年人。接触儿童的感染风险受与索引病例的传染性、接触条件以及儿童自身相关的多种因素调节。本综述旨在描述儿童潜伏性结核感染和结核病的具体诊断及治疗特点。