Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA.
Curr Biol. 2011 May 10;21(9):R302-4. doi: 10.1016/j.cub.2011.03.051.
New evidence suggests that katanin - best known for severing microtubules in their more stable regions - localizes at the leading edge of migratory cells and trims microtubules at their dynamic plus ends.
新的证据表明,katanin——以在其更稳定的区域切断微管而闻名——定位于迁移细胞的前缘,并在其动态的正端修剪微管。