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分枝杆菌免疫重建炎症综合征：HIV 感染期间急性间质性肾炎的一个病因。

Mycobacterial-immune reconstitution inflammatory syndrome: a cause of acute interstitial nephritis during HIV infection.

机构信息

Department of Infectious Tropical Diseases, Université Toulouse III, Toulouse cedex 9, France.

出版信息

Nephrol Dial Transplant. 2011 Jul;26(7):2403-6. doi: 10.1093/ndt/gfr197. Epub 2011 May 5.

DOI:10.1093/ndt/gfr197
PMID:21551092
Abstract

Kidney injury during HIV infection encompasses a wide variety of disorders, including acute interstitial nephritis. We report a case of acute granulomatous interstitial nephritis related to a mycobacterial-triggered immune reconstitution inflammatory syndrome (IRIS) in an HIV-infected patient. IRIS is an emerging health concern during HIV infection and should be considered in the diagnostic frame of acute renal failure during immune restoration.

摘要

在人类免疫缺陷病毒（HIV）感染期间，肾脏损伤包括多种疾病，包括急性间质性肾炎。我们报告了一例 HIV 感染患者中与分枝杆菌触发的免疫重建炎症综合征（IRIS）相关的急性肉芽肿性间质性肾炎。IRIS 是 HIV 感染期间出现的一个健康问题，在免疫重建期间发生急性肾衰竭的诊断框架中应考虑到这一点。

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