Department of Internal Medicine, Division of Infectious Disease, University of New Mexico Hospital Health Science Center, Albuquerque, NM, USA.
Int J STD AIDS. 2020 Aug;31(9):911-913. doi: 10.1177/0956462420926881. Epub 2020 Jul 1.
Disseminated is a rare opportunistic infection reported most commonly in advanced human immunodeficiency virus (HIV) infection. Treatment can be further complicated by the occurrence of severe immune reconstitution inflammatory syndrome (IRIS). We present the first case of disseminated multi-drug-resistant in the setting of advanced HIV, complicated by IRIS in the form of granulomatous interstitial nephritis causing acute renal failure. This case highlights the importance of recognizing rare complications of IRIS, as delays in therapy can be life threatening.
播散性是一种罕见的机会性感染，在晚期人类免疫缺陷病毒（HIV）感染中最为常见。治疗可能因严重的免疫重建炎症综合征（IRIS）的发生而变得更加复杂。我们报告了首例晚期 HIV 合并 IRIS 表现为肉芽肿性间质性肾炎导致急性肾衰竭的播散性多药耐药的病例。本病例强调了认识 IRIS 罕见并发症的重要性，因为延迟治疗可能危及生命。
