注意 F-18 FDG PET 上弥漫性皮下结节的播散性肉样瘤病。

Be aware of disseminated sarcoidosis with diffuse subcutaneous nodules on F-18 FDG PET.

机构信息

Department of Radiology, University of Mississippi Medical Center, Jackson, MS, USA.

出版信息

Clin Nucl Med. 2011 Jun;36(6):e42-4. doi: 10.1097/RLU.0b013e31821739cf.

PMID:21552015

Abstract

Sarcoidosis is a multisystem granulomatous disorder of unknown etiology that typically affects young adults. Definitive diagnosis requires compatible clinical and radiologic manifestations and histopathologic detection of noncaseating granulomas. In recent years, F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) has been proposed to play a role in the diagnosis and management of sarcoidosis. Although disseminated sarcoidosis has been reported in nearly all organs including the skin, subcutaneous sarcoidosis is relatively rare with few reports using F-18 FDG PET. We report a case of disseminated sarcoidosis with diffuse subcutaneous nodules demonstrating avid F-18 FDG uptake on PET.

摘要

结节病是一种病因不明的多系统肉芽肿性疾病，通常影响年轻人。明确的诊断需要兼容的临床和影像学表现以及非干酪样肉芽肿的组织病理学检测。近年来，18F 氟脱氧葡萄糖（FDG）正电子发射断层扫描（PET）已被提议在结节病的诊断和治疗中发挥作用。虽然结节病已在包括皮肤在内的几乎所有器官中广泛报道，但皮下结节病相对罕见，使用 18F FDG PET 的报道较少。我们报告一例弥漫性结节病，弥漫性皮下结节在 PET 上显示摄取 FDG 增多。