Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Road, Singapore.
Clin Nucl Med. 2013 Mar;38(3):205-8. doi: 10.1097/RLU.0b013e31827a22e0.
Scar involvement is a rare but characteristic cutaneous manifestation of sarcoidosis. The concurrent presence of FDG-avid lymphadenopathy and scar involvement (the "scar sign") is a useful finding on FDG PET/CT to suggest sarcoidosis, especially when biopsy specimens are difficult to obtain. A 46-year-old woman who presented with fever, cough, and weight loss was found to have mediastinal and hilar lymphadenopathy on chest radiography and CT scan. FDG PET/CT scan showed FDG-avid lower cervical, mediastinal, hilar, and inguinal lymphadenopathy. There was also increased FDG uptake along an old hysterectomy scar. Mediastinoscopy and nodal biopsy revealed noncaseating granulomas compatible with sarcoidosis.
瘢痕累及是结节病的一种罕见但特征性的皮肤表现。在 FDG PET/CT 上，FDG 摄取的淋巴结病和瘢痕累及（“瘢痕征”）同时存在是提示结节病的有用发现，尤其是在难以获得活检标本时。一位 46 岁的女性因发热、咳嗽和体重减轻就诊，胸部 X 线和 CT 扫描发现纵隔和肺门淋巴结肿大。FDG PET/CT 扫描显示 FDG 摄取的下颈部、纵隔、肺门和腹股沟淋巴结肿大。子宫切除术的旧瘢痕处也有 FDG 摄取增加。纵隔镜检查和淋巴结活检显示非干酪样肉芽肿，符合结节病。
