From the Departments of *Nuclear Medicine, and †Internal Medicine II, Hokkaido University Graduate School of Medicine; and ‡Department of Pathology, KKR Sapporo Medical Center, Sapporo, Hokkaido, Japan.
Clin Nucl Med. 2014 Jul;39(7):648-9. doi: 10.1097/RLU.0000000000000488.
We report about the usefulness of F-FDG PET for the detection and therapy response evaluation of renal sarcoidosis. A 55-year-old woman presented with a condition diagnosed with pulmonary and ocular sarcoidosis 2 years before having anemia and acute deterioration of renal function. FDG PET revealed diffuse increased FDG uptake in both kidneys and the spleen. Histopathologic examination of a renal biopsy sample revealed granulomatous interstitial nephritis with sarcoidosis. After methylprednisolone treatment, the abnormal FDG uptake resolved completely with improvement of symptoms. FDG PET is a useful tool to detect active sarcoidosis regions and to monitor treatment efficacy.
我们报告了 F-FDG PET 在检测和治疗反应评估肾结节病中的作用。一名 55 岁女性在出现贫血和肾功能急性恶化前 2 年被诊断为患有肺和眼结节病。FDG PET 显示双侧肾脏和脾脏弥漫性 FDG 摄取增加。肾活检样本的组织病理学检查显示伴有结节病的肉芽肿性间质性肾炎。经甲基强的松龙治疗后，症状改善，异常 FDG 摄取完全消退。FDG PET 是一种有用的工具，可以检测活性结节病区域并监测治疗效果。
