Departamento de Clínica Médica Laboratório de Fisiologia do Exercício, Divisão de Cardiologia, Faculdade de Medicina de Ribeirão Preto, USP, Brazil.
Arq Bras Cardiol. 2011 Jul;97(1):59-64. doi: 10.1590/s0066-782x2011005000056. Epub 2011 May 6.
Chronic heart failure (HF) is a syndrome characterized by reduced cardiac output in relation to the metabolic needs of the organism, as well as metabolic and neurohormonal axis abnormalities. Symptoms such as fatigue and dyspnoea are notorious and stress tests are widely used to assess functional capacity, prognosis and effectiveness of therapeutic interventions in this syndrome.
To evaluate the reproducibility of the six-minute walk test (6MW) in patients with HF and correlate the magnitude of the variables reached at peak exercise of the 6MWT with a cardiopulmonary exercise test (CPET).
We studied 16 patients (12 men and 4 women) diagnosed with HF FC I-II (NYHA). The volunteers underwent two 6MWT (6MWT'1 and 6MWT'2) with 30-minute interval between them; then, they underwent a maximum CPET.
All variables obtained in the two 6MWT' proved to be significant with high correlations: distance walked (DW) (r = 0.93, p < 0.0001), heart rate (HR) (r = 0.89, p < 0.0001), oxygen consumption (VO2) (r = 0.93, p < 0.0001) and scale of perceived exertion (r = 0.85, p < 0.0001). In turn, all variables analyzed in the 6MWT' showed significant and moderate correlations with the variables obtained from the CPET, namely: peak HR (r = 0.66; p = 0.005); VO2 (r = 0.57; p = 0.02) and VO2 in the CPET and DT in the 6MWT'2 (r = 0.70; p = 0.002).
The 6MWT was reproducible in this group of patients with HF (NYHA - I-II) and correlated with the CPET. Therefore, it is a tool for reliable evaluation, and a suitable, safe and low-cost alternative for the prescription of aerobic exercise in patients with HF.
慢性心力衰竭(HF)是一种以心输出量与机体代谢需求不匹配为特征的综合征,以及代谢和神经激素轴异常。疲劳和呼吸困难等症状是众所周知的,运动试验被广泛用于评估该综合征的功能能力、预后和治疗干预效果。
评估心力衰竭患者六分钟步行试验(6MWT)的可重复性,并将 6MWT 峰值运动时达到的变量与心肺运动试验(CPET)相关联。
我们研究了 16 名(12 名男性和 4 名女性)被诊断为 HF FC I-II(NYHA)的患者。志愿者在两次 6MWT(6MWT'1 和 6MWT'2)之间间隔 30 分钟;然后,他们进行了最大 CPET。
两次 6MWT'中获得的所有变量均具有显著相关性:步行距离(DW)(r = 0.93,p < 0.0001)、心率(HR)(r = 0.89,p < 0.0001)、耗氧量(VO2)(r = 0.93,p < 0.0001)和感知用力程度(r = 0.85,p < 0.0001)。反过来,6MWT'中分析的所有变量与 CPET 获得的变量均显示出显著的中度相关性,即:峰值 HR(r = 0.66;p = 0.005);VO2(r = 0.57;p = 0.02)和 CPET 中的 VO2 和 6MWT'2 中的 DT(r = 0.70;p = 0.002)。
该组心力衰竭(NYHA - I-II)患者的 6MWT 具有可重复性,并与 CPET 相关。因此,它是一种可靠评估的工具,也是心力衰竭患者有氧运动处方的一种合适、安全和低成本的替代方法。