脑微出血的叶分布：鹿特丹扫描研究
Lobar distribution of cerebral microbleeds: the Rotterdam Scan Study.
作者信息
Mesker Dymph J, Poels Mariëlle M F, Ikram M Arfan, Vernooij Meike W, Hofman Albert, Vrooman Henri A, van der Lugt Aad, Breteler Monique M B
机构信息
Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
出版信息
Arch Neurol. 2011 May;68(5):656-9. doi: 10.1001/archneurol.2011.93.
OBJECTIVE
To investigate the distribution of lobar microbleeds over the different lobes, taking into account lobar volume and clustering effects of multiple microbleeds.
DESIGN
Population-based, cross-sectional analysis.
SETTING
The Rotterdam Scan Study.
PARTICIPANTS
A total of 198 persons (age range, 61-95 years) with lobar microbleeds.
MAIN OUTCOME MEASURES
Distribution of microbleeds over different lobes.
RESULTS
We found that lobar cerebral microbleeds occurred significantly more often in the temporal lobe, a region known to be more affected in cerebral amyloid angiopathy.
CONCLUSION
This study corroborates the presumed association of lobar microbleeds with cerebral amyloid angiopathy.
目的
考虑脑叶体积和多个微出血灶的聚集效应，研究脑叶微出血灶在不同脑叶中的分布情况。
设计
基于人群的横断面分析。
地点
鹿特丹扫描研究。
参与者
共有198例（年龄范围61 - 95岁）存在脑叶微出血灶的患者。
主要观察指标
微出血灶在不同脑叶中的分布。
结果
我们发现脑叶微出血灶在颞叶的发生频率显著更高，颞叶是已知在脑淀粉样血管病中受影响更严重的区域。
结论
本研究证实了脑叶微出血灶与脑淀粉样血管病之间的假定关联。
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