Rockstroh Jürgen K, Peters Lars, Wedemeyer Heiner
Department of Medicine I, University of Bonn, Germany.
Antivir Ther. 2011;16(3):287-9. doi: 10.3851/IMP1787.
Liver disease is one of the leading causes of death in HIV-infected individuals from Europe and North America and has been attributed mainly to coinfection with hepatotropic viruses. Little data, however, has so far become available on liver disease in HIV-infected individuals from Africa. Results from a first study on liver disease staging by Fibroscan(®) in a large group of HIV-infected patients from rural Uganda suggest unexpectedly high rates of advanced fibrosis. These results were independent from hepatitis status, initiating a discussion on the need for future liver disease monitoring in these particular patient groups.
肝病是欧洲和北美的艾滋病毒感染者的主要死因之一，主要归因于与嗜肝病毒的合并感染。然而，目前关于非洲艾滋病毒感染者肝病的可用数据很少。在乌干达农村的一大群艾滋病毒感染患者中，第一项关于通过Fibroscan（®）进行肝病分期的研究结果显示，晚期纤维化的发生率出乎意料地高。这些结果与肝炎状况无关，引发了关于在这些特定患者群体中未来进行肝病监测必要性的讨论。
