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一名患有未经治疗的法洛四联症的卢旺达患者出现右侧肢体无力。

Right-sided weakness in a Rwandan patient with untreated Tetralogy of Fallot.

作者信息

Tshilombo Sylvain, Bilugan Romeo, Feeney Amanda, Im Jonathan, Kuntz Heather M, Gandhi Kavita, Barcega Besh, Babane Jean Felix, Ndebwanimana Vincent, Guptill Mindi

机构信息

Department of Anesthesia, Emergency Medicine and Critical Care, University of Rwanda, Kigali, Rwanda.

Department of Emergency Medicine, Loma Linda University School of Medicine, 11234 Anderson Street, Loma Linda, CA, 92354, USA.

出版信息

Int J Emerg Med. 2023 Mar 14;16(1):19. doi: 10.1186/s12245-023-00494-0.

Abstract

BACKGROUND

Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease encountered in pediatrics with surgical repair being the definitive treatment. Long-term survival after surgical repair has improved; however, reported mortality rates in untreated TOF are significant. Associated complications include neurological sequelae such as brain abscess and stroke. In countries without early intervention for congenital heart disease (including TOF), delayed presentations and complications require recognition by healthcare workers.

CASE PRESENTATION

A 22-year-old male with a history of untreated TOF presented to Rwanda's tertiary university hospital, University Teaching Hospital of Kigali, with acute right-sided hemiparesis. Diagnostic imaging identified a left-sided brain lesion consistent with brain abscess and cardiac mass, concerning endocardial vegetation. He was managed with intravenous antibiotics but subsequently died due to complications of septicemia.

DISCUSSION

In countries where surgical repair of TOF is not available, early recognition and medical management are key in temporizing the development of devastating sequelae. Describing the prevalence of CHD in Rwanda is urgent, requiring further research by which effective prevention and treatment strategies can be developed.

摘要

背景

法洛四联症(TOF)是儿科中最常见的青紫型先天性心脏病,手术修复是其确定性治疗方法。手术修复后的长期生存率有所提高;然而,未经治疗的TOF报告的死亡率很高。相关并发症包括神经后遗症,如脑脓肿和中风。在没有对先天性心脏病(包括TOF)进行早期干预的国家,延迟就诊和并发症需要医护人员予以识别。

病例介绍

一名22岁有未经治疗的TOF病史的男性前往卢旺达的三级大学医院基加利大学教学医院就诊,出现急性右侧偏瘫。诊断性影像学检查发现左侧脑病变,符合脑脓肿和心脏肿块,考虑为心内膜赘生物。他接受了静脉抗生素治疗,但随后因败血症并发症死亡。

讨论

在无法进行TOF手术修复的国家,早期识别和药物治疗是延缓严重后遗症发展的关键。迫切需要描述卢旺达先天性心脏病的患病率,这需要进一步研究以制定有效的预防和治疗策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31a0/10012476/831b1356ca7f/12245_2023_494_Fig1_HTML.jpg

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