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预防中心静脉导管相关血流感染:消除可预防伤害的征途。

Prevention of central line-associated bloodstream infections: a journey toward eliminating preventable harm.

机构信息

Departments of Anesthesiology and Critical Care Medicine, Quality and Safety Research Group, John Hopkins University School of Medicine, Baltimore, MD, USA,

出版信息

Curr Infect Dis Rep. 2011 Aug;13(4):343-9. doi: 10.1007/s11908-011-0186-8.

DOI:10.1007/s11908-011-0186-8
PMID:21556693
Abstract

Central line-associated blood stream infections (CLABSI) are among the most common, lethal, and costly health care-associated infections. Recent large collaborative quality improvement efforts have achieved unprecedented and sustained reductions in CLABSI rates and demonstrate that these infections are largely preventable, even for exceedingly ill patients. The broad acceptance that zero CLABSI rates are an achievable goal has motivated and stimulated diverse groups of stakeholders, including public and private groups to develop policy tools and to mobilize their local constituents toward achieving this goal. Nevertheless, attributing reductions in CLABSI rates achieved by multifaceted quality improvement efforts solely to the use of checklists to ensure adherence with appropriate infection control practices is an easily made but crucial mistake. National CLABSI prevention is a shared responsibility and creating novel partnerships between government agencies, health care industry, and consumers is critical to making and sustaining progress in achieving the goals toward eliminating CLABSI.

摘要

中心静脉导管相关性血流感染(CLABSI)是最常见、最致命和最昂贵的医疗保健相关感染之一。最近,大规模的合作质量改进努力取得了前所未有的、持续的 CLABSI 率降低,并证明这些感染在很大程度上是可以预防的,即使是对病情极其严重的患者也是如此。广泛认为零 CLABSI 率是一个可以实现的目标,这激发和激励了包括公共和私营团体在内的不同利益相关者群体制定政策工具,并动员其当地成员努力实现这一目标。然而,将多方面质量改进努力所取得的 CLABSI 率降低归因于检查表的使用,以确保遵守适当的感染控制措施,这是一个很容易犯但至关重要的错误。国家 CLABSI 预防是一项共同的责任,在政府机构、医疗保健行业和消费者之间建立新的伙伴关系对于在实现消除 CLABSI 的目标方面取得和维持进展至关重要。

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Impact of a statewide intensive care unit quality improvement initiative on hospital mortality and length of stay: retrospective comparative analysis.全州范围内重症监护病房质量改进计划对医院死亡率和住院时间的影响:回顾性对比分析。
BMJ. 2011 Jan 28;342:d219. doi: 10.1136/bmj.d219.
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The Rhode Island ICU collaborative: a model for reducing central line-associated bloodstream infection and ventilator-associated pneumonia statewide.罗德岛重症监护病房协作项目:一个在全州范围内减少中心静脉导管相关血流感染和呼吸机相关性肺炎的模式。
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Hospital Board Checklist to improve culture and reduce central line-associated bloodstream infections.
医院委员会改善文化及减少中心静脉导管相关血流感染的检查表。
Jt Comm J Qual Patient Saf. 2010 Nov;36(11):525-8. doi: 10.1016/s1553-7250(10)36078-8.
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Moving toward elimination of healthcare-associated infections: a call to action.迈向消除医疗保健相关感染:行动呼吁。
Am J Infect Control. 2010 Nov;38(9):671-5. doi: 10.1016/j.ajic.2010.09.001.
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The clinical and prognostic importance of positive blood cultures in adults.成人血培养阳性的临床和预后意义。
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Anti-infective external coating of central venous catheters: a randomized, noninferiority trial comparing 5-fluorouracil with chlorhexidine/silver sulfadiazine in preventing catheter colonization.中心静脉导管抗感染外涂层:一项比较氟尿嘧啶与氯己定/磺胺嘧啶银预防导管定植的随机、非劣效性试验。
Crit Care Med. 2010 Nov;38(11):2095-102. doi: 10.1097/CCM.0b013e3181f265ba.
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Antibiotic lock solutions for the prevention of catheter-related bacteraemia in haemodialysis patients.抗生素封管溶液预防血液透析患者导管相关菌血症。
Hong Kong Med J. 2010 Aug;16(4):269-74.
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