Pathologie Végétale (UMR077 INRA-Agrocampus Ouest-Université d'Angers), Beaucouzé, France.
Adv Exp Med Biol. 2011;715:71-89. doi: 10.1007/978-94-007-0940-9_5.
The family Xanthomonadaceae is a wide-spread family of bacteria belonging to the gamma subdivision of the Gram-negative proteobacteria, including the two plant-pathogenic genera Xanthomonas and Xylella, and the related genus Stenotrophomonas. Adhesion is a widely conserved virulence mechanism among Gram-negative bacteria, no matter whether they are human, animal or plant pathogens, since attachment to the host tissue is one of the key early steps of the bacterial infection process. Bacterial attachment to surfaces is mediated by surface structures that are anchored in the bacterial outer membrane and cover a broad group of fimbrial and non-fimbrial structures, commonly known as adhesins. In this chapter, we discuss recent findings on candidate adhesins of plant-pathogenic Xanthomonadaceae, including polysaccharidic (lipopolysaccharides, exopolysaccharides) and proteineous structures (chaperone/usher pili, type IV pili, autotransporters, two-partner-secreted and other outer membrane adhesins), their involvement in the formation of biofilms and their mode of regulation via quorum sensing. We then compare the arsenals of adhesins among different Xanthomonas strains and evaluate their mode of selection. Finally, we summarize the sparse knowledge on specific adhesin receptors in plants and the possible role of RGD motifs in binding to integrin-like plant molecules.
黄单胞菌科是广泛分布的细菌家族，属于革兰氏阴性变形菌的γ亚群，包括两个植物病原性属黄单胞菌属和木质部杆菌属，以及相关的嗜麦芽寡养单胞菌属。黏附是革兰氏阴性细菌普遍存在的毒力机制，无论它们是人类、动物还是植物病原体，因为附着在宿主组织上是细菌感染过程的关键早期步骤之一。细菌附着在表面是由锚定在细菌外膜上并覆盖广泛的菌毛和非菌毛结构的表面结构介导的，通常称为黏附素。在本章中，我们讨论了植物病原性黄单胞菌科候选黏附素的最新发现，包括多糖（脂多糖、胞外多糖）和蛋白结构（伴侣/usher 菌毛、IV 型菌毛、自转运蛋白、双组分分泌和其他外膜黏附素），它们在生物膜形成中的作用及其通过群体感应的调节方式。然后，我们比较了不同黄单胞菌菌株之间黏附素的武器库，并评估了它们的选择方式。最后，我们总结了关于植物中特定黏附素受体的稀疏知识，以及 RGD 基序在与整合素样植物分子结合中的可能作用。
