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脊髓硬膜外脂肪增多症:复发性和缓解性轻截瘫的一种罕见病因。

Spinal epidural lipomatosis: An unusual cause of relapsing and remitting paraparesis.

作者信息

Rajput Dinesh, Srivastava Arun K, Kumar Raj

机构信息

Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

出版信息

J Pediatr Neurosci. 2010 Jul;5(2):150-2. doi: 10.4103/1817-1745.76117.

Abstract

Epidural lipomatosis is a rare entity to cause spinal cord compression and neurological deficits. This is usually associated with excess of steroids in the body either because of endogenous source as in Cushings disease or exogenous intake as in some diseases like systemic lupus erythematosus, in some endocrinopathies or in morbid obesity. But in some cases no cause has been found. Such idiopathic cases of spinal epidural lipomatosis have also been reported. Here, we report a case of idiopathic spinal epidural lipomatosis with relapsing and remitting paraparesis which is quite unusual. Treatment depends upon neurological status of the patient. We operated the patient as he had significant neurological compromise and he improved significantly.

摘要

硬膜外脂肪增多症是一种导致脊髓压迫和神经功能缺损的罕见病症。这通常与体内类固醇过量有关,其原因要么是内源性的,如库欣病,要么是外源性摄入,如系统性红斑狼疮等某些疾病、一些内分泌疾病或病态肥胖症。但在某些情况下,病因尚未找到。也有此类特发性脊髓硬膜外脂肪增多症的病例报道。在此,我们报告一例特发性脊髓硬膜外脂肪增多症,伴有复发和缓解的双侧下肢轻瘫,这相当不寻常。治疗取决于患者的神经状态。由于该患者存在严重的神经功能损害,我们对其进行了手术,术后他有显著改善。

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