Biomedical Optics Research Laboratory, Clinic of Neonatology, University Hospital Zürich, Frauenklinikstrasse 10, 8091 Zurich, Switzerland.
J Mol Model. 2012 Feb;18(2):607-9. doi: 10.1007/s00894-011-1081-9. Epub 2011 May 11.
The concept called Knowledge is a measure of the quality of genetically transferred information. Its usefulness is demonstrated quantitatively in a Monte-Carlo simulation on critical steps in a origin of life model. The model describes the origin of a bio-like genetic apparatus by a long sequence of physical-chemical steps: it starts with the presence of a self-replicating oligomer and a specifically structured environment in time and space that allow for the formation of aggregates such as assembler-hairpins-devices and, at a later stage, an assembler-hairpins-enzyme device-a first translation machine.
“知识”这一概念是衡量遗传信息质量的指标。它的有用性在一个生命起源模型关键步骤的蒙特卡罗模拟中得到了定量证明。该模型通过一系列物理化学步骤描述了类生物遗传装置的起源：它从一个自我复制的低聚物和一个在时间和空间上具有特定结构的环境开始，这些环境允许形成聚集物，如组装发夹设备，以及在稍后阶段，形成组装发夹-酶设备，即第一个翻译机器。
