Othersen H B, DeLorimer A, Hrabovsky E, Kelalis P, Breslow N, D'Angio G J
Medical University Hospital, Charleston, SC.
J Pediatr Surg. 1990 Mar;25(3):330-1. doi: 10.1016/0022-3468(90)90079-o.
Because lymph node (LN) involvement continues to be an adverse prognostic factor in the later National Wilms' Tumor Study (NWTS) trials, the NWTS-3 Surgical Committee undertook a project to determine the accuracy of the present method of sampling. The committee concludes that: (1) there is a relatively low potential error rate (less than 10%) that would comprise adequate care when a policy of LN sampling is followed; (2) this does not encourage routine radical LN dissections in Wilms' tumor patients because of the well-known morbidities associated with that procedure; and (3) LN sampling in all Wilms' tumor patients should be performed with a high index of suspicion present in the mind of the operating surgeon.
