Institute of Biology/Applied Genetics, Dahlem Centre of Plant Sciences, Freie Universität Berlin, Albrecht-Thaer-Weg 6, D-14195 Berlin, Germany.
Eur J Cell Biol. 2012 Apr;91(4):246-56. doi: 10.1016/j.ejcb.2011.02.009. Epub 2011 May 10.
The discovery of cytokinin receptors of Arabidopsis thaliana ten years ago was a milestone in plant hormone research. Since then, research has yielded insights into the biochemical properties and functions of these sensor histidine kinases. Their affinities to both trans-zeatin and isopentenyladenine are in the low nM range. Cytokinin ribosides, cis-zeatin and thidiazuron were established as compounds with genuine cytokinin activity and the first cytokinin antagonists were identified. Numerous functions of cytokinin receptors in plant development, as well as in the plant's responses to the environment, have been elucidated and are summarized. Finally, we address the question how the receptors have evolved during plant evolution.
十年前，拟南芥细胞分裂素受体的发现是植物激素研究的一个里程碑。从那时起，研究揭示了这些感应组氨酸激酶的生化特性和功能。它们对玉米素核苷和异戊烯基腺嘌呤的亲和力均在低 nM 范围内。细胞分裂素核苷、顺式玉米素和噻二唑隆被确定为具有真正细胞分裂素活性的化合物，并且首次鉴定出细胞分裂素拮抗剂。细胞分裂素受体在植物发育以及植物对环境的响应中的许多功能已经被阐明，并进行了总结。最后，我们探讨了受体在植物进化过程中是如何进化的。
