Department of Occupational Medicine, Slagelse Hospital, DK-4200 Slagelse, Denmark.
Occup Med (Lond). 2011 Sep;61(6):437-9. doi: 10.1093/occmed/kqr040. Epub 2011 May 11.
Workers exposed to pigs can develop meningitis, sepsis or endocarditis due to infection with Streptococcus suis transmitted from pigs to man.
To estimate the risk of these diseases.
We used the Occupational Hospitalization Register (OHR) which holds information about occupation and hospital treatments for all adults in Denmark. A dynamic population of male workers exposed to pigs was identified every year from 1995 to 2006 by occupational and industrial groups. First hospital treatment or death in the following year due to meningitis, sepsis or endocarditis was identified by ICD-10 codes from the OHR. By comparison with all other economically active men in Denmark, the standardized incidence ratio (SIR) was calculated for these diseases.
Among those exposed, we observed 32 cases of meningitis, sepsis and endocarditis during 140,118 person-years. In the reference group, we observed 2680 cases during 15,209,394 person-years. The SIR of the exposed group was 1.35 (95% CI: 0.95-1.92). Among the 32 cases, 7 cases of meningitis and sepsis were specified as caused by infection with streptococci. The SIR for these seven cases was 2.4 (95% CI: 1.1-5.0).
Our study did not find that workers exposed to pigs had an overall increased risk of developing meningitis, sepsis or endocarditis.
接触猪的工人可能会因猪传播给人类的猪链球菌感染而患上脑膜炎、败血症或心内膜炎。
评估这些疾病的风险。
我们使用了职业住院登记（OHR），该登记包含丹麦所有成年人的职业和住院治疗信息。每年通过职业和工业群体确定接触过猪的男性工人的动态人群。通过 OHR 的 ICD-10 代码确定次年因脑膜炎、败血症或心内膜炎首次住院治疗或死亡的情况。通过与丹麦所有其他经济活跃男性进行比较，计算这些疾病的标准化发病比（SIR）。
在接触者中，我们在 140118 人年中观察到 32 例脑膜炎、败血症和心内膜炎。在对照组中，我们在 15209394 人年中观察到 2680 例。暴露组的 SIR 为 1.35（95%CI：0.95-1.92）。在 32 例中，有 7 例脑膜炎和败血症被指定为由链球菌感染引起。这 7 例的 SIR 为 2.4（95%CI：1.1-5.0）。
我们的研究没有发现接触猪的工人患脑膜炎、败血症或心内膜炎的总体风险增加。
