用于一期筋膜修复的兔模型中轻质合成材料的收缩及生物力学评估
Shrinkage and biomechanical evaluation of lightweight synthetics in a rabbit model for primary fascial repair.
作者信息
Ozog Yves, Konstantinovic Maja L, Werbrouck Erika, De Ridder Dirk, Edoardo Mazza, Deprest Jan
机构信息
Center for Surgical Technologies, Faculty of Medicine, Universitair Ziekenhuis Gasthuisberg Leuven, Katholieke Universiteit Leuven, Minderbroedersstraat 19, Box 1034, 3000 Leuven, Belgium.
出版信息
Int Urogynecol J. 2011 Sep;22(9):1099-108. doi: 10.1007/s00192-011-1440-1. Epub 2011 May 12.
INTRODUCTION AND HYPOTHESIS
The experiment evaluated different lightweights (<32 g/m(2)) in terms of shrinkage and biomechanics.
METHODS
PP-8 (polypropylene of 7.6 g/m(2)), PP-s (PP-8 with absorbable sheets), PP-32 (PP with absorbable fibers; 32.0 g/m(2)) and polyvinylidinefluoride (PVDF; 24.9 g/m(2)) augmented primary sutured repairs of the anterior abdominal wall in a total of 40 rabbits. Rabbits were implanted by only one type of mesh at four abdominal sites. After 7, 14, 30, 60 and 120 days, 2 rabbits were sacrificed per group. Three additional unoperated rabbits were used as controls. Shrinkage and uni-axial tensiometry were evaluated.
RESULTS
PP-s implants wrinkled in 70%. PP-32 did not shrink whereas PP-8 and PVDF shrank by 20%. Explants were as strong as the controls; however, they differed in compliance. At lower stress, the tested materials were equally stiff.
CONCLUSIONS
The biomechanical behaviour of the tested lightweights does not mimic that of native controls. Weight reduction does not prevent shrinkage.
引言与假设
本实验从收缩率和生物力学方面评估了不同的轻质材料（<32 g/m²）。
方法
PP - 8（7.6 g/m²的聚丙烯）、PP - s（带有可吸收片材的PP - 8）、PP - 32（带有可吸收纤维的PP；32.0 g/m²）和聚偏二氟乙烯（PVDF；24.9 g/m²）用于加强40只兔子的前腹壁一期缝合修复。兔子在四个腹部位置仅植入一种类型的补片。在7天、14天、30天、60天和120天后，每组处死2只兔子。另外3只未手术的兔子作为对照。评估收缩率和单轴拉伸测量。
结果
70%的PP - s植入物出现褶皱。PP - 32没有收缩，而PP - 8和PVDF收缩了20%。取出的植入物与对照一样坚固；然而，它们在顺应性方面有所不同。在较低应力下，测试材料的硬度相同。
结论
测试的轻质材料的生物力学行为与天然对照不同。减轻重量并不能防止收缩。
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