Centre d'Evaluation et d'Information sur la Pharmacodépendance, CEIP-Addictovigilance, Pharmacologie Clinique, Hôpital Timone, Marseille, France.
Fundam Clin Pharmacol. 2012 Aug;26(4):549-56. doi: 10.1111/j.1472-8206.2011.00950.x. Epub 2011 May 12.
The objective of the study was to determine which psychoactive prescription drugs are illegally obtained and through which ways of acquisition. OPPIDUM is an annual national study. It is based on specialized care centers that included subjects presenting a drug dependency or under opiate maintenance treatment. All their psychoactive substances consumed are reported. This work focuses on the different ways of acquisition specially the illegal ways of acquisition (bought on the street, forged prescription, stolen, given, internet). For each medication illegally obtained, a ratio has been calculated (number of illegal acquisitions divided by the number of described acquisitions). In 2008, 5542 subjects have been included and have described the consumption of 11 027 substances including 63.8% of prescription drugs. Among them, 11% were illegally obtained. The different illegal acquisition ways were 'street market' (77.6%), 'gift' (16.6%), 'theft' (2.3%), 'forged prescription' (2.3%), and 'internet' (0.7%). The third first drugs illegally obtained were high dosage buprenorphine, methadone, and clonazepam. Some prescription drugs, less consumed, have an important ratio of illegal acquisition like ketamine, flunitrazepam, morphine, trihexyphenidyl, or methylphenidate. This study confirms that theft, forged prescription and internet are few used and permits to highlight diversion of prescription drugs. It is important to inform healthcare professionals on the different prescription drugs that are illegally obtained.
这项研究的目的是确定哪些精神活性处方药物是非法获得的,以及通过哪些途径获得的。OPPIDUM 是一项年度全国性研究。它基于专门的护理中心,包括有药物依赖或接受阿片类药物维持治疗的患者。所有他们消耗的精神活性物质都有报告。这项工作主要关注的是不同的获取途径,特别是非法获取途径(在街上购买、伪造处方、被盗、赠送、互联网)。对于每种非法获得的药物,都计算了一个比值(非法获取的数量除以描述的获取数量)。2008 年,共纳入 5542 名患者,他们描述了 11027 种物质的消费情况,其中包括 63.8%的处方药物。其中,11%是非法获得的。不同的非法获取途径包括“街头市场”(77.6%)、“礼物”(16.6%)、“盗窃”(2.3%)、“伪造处方”(2.3%)和“互联网”(0.7%)。非法获得的前三种药物分别是高剂量丁丙诺啡、美沙酮和氯硝西泮。一些较少消耗的处方药物,其非法获取的比例也很高,如氯胺酮、氟硝西泮、吗啡、苯海索或哌甲酯。这项研究证实,盗窃、伪造处方和互联网的使用很少,这有助于突出处方药物的转移。向医疗保健专业人员通报非法获取的不同处方药物非常重要。