鉴定埃及伊蚊中的 8 个单核苷酸多态性标记。

Characterization of eight single nucleotide polymorphism markers in Aedes aegypti.

机构信息

Departamento de Parasitologia, Instituto de Biociências, Universidade Estadual Paulista, Caixa Postal 510, 18618-000, Botucatu, São Paulo, Brazil.

出版信息

Mol Ecol Resour. 2009 Jan;9(1):114-6. doi: 10.1111/j.1755-0998.2008.02282.x. Epub 2008 Sep 15.

DOI:10.1111/j.1755-0998.2008.02282.x

PMID:21564575

Abstract

Sequencing of part of seven genes from Aedes aegypti collected in 16 Brazilian cities revealed the existence of 53 single nucleotide polymorphisms (SNPs), representing one SNP every 52 base pairs. From these 53 SNPs, we selected eight that are independent and highly polymorphic. We describe the use of these markers for differentiation of Brazilian populations of A. aegypti. These are the first SNPs developed for delineating population structure in A. aegypti, and will be a useful complement to epidemiological studies.

摘要

对从 16 个巴西城市采集的埃及伊蚊部分的 7 个基因进行测序，揭示了存在 53 个单核苷酸多态性（SNP），代表每 52 个碱基对存在一个 SNP。从这 53 个 SNP 中，我们选择了 8 个独立且高度多态性的 SNP。我们描述了这些标记在区分巴西埃及伊蚊种群中的应用。这些是为描绘埃及伊蚊种群结构而开发的第一批 SNP，将成为流行病学研究的有益补充。