慢性光化性皮炎：25 年单中心分析。

Chronic actinic dermatitis: an analysis at a single institution over 25 years.

机构信息

Photomedicine Section, Charles C. Harris Skin and Cancer Pavilion, Ronald O. Perelman Department of Dermatology, New York University School of Medicine, NY, USA.

出版信息

Dermatitis. 2011 May;22(3):147-54.

PMID:21569744

Abstract

BACKGROUND

Chronic actinic dermatitis (CAD) is a rare photosensitivity disorder with scant epidemiologic data.

OBJECTIVE

To evaluate demographic data and results of photopatch and patch tests over a 25-year period.

METHODS

Retrospective chart review of patients with CAD from 1993 to 2009.

RESULTS

Forty patients had a mean age of 57.8 years, and 27 (67.5%) were men. Twelve patients (30%) were skin types I and II, and 17 (42.5%) were skin types V and VI. Nine patients (22.5%) were younger than 50 years, and 4 of these (44.4%) were men. One of the nine patients (11.1%) was skin type I, and 4 (44.4%) were skin types V and VI. Carba mix and para-phenylenediamine were the two most commonly positive agents in patch tests. Sunscreens and plants and plant derivatives were the most commonly positive agents in photopatch tests.

CONCLUSIONS

Our findings suggest a trend of two new classes of North American patients at our institution being diagnosed with CAD-younger women with skin types IV to VI and older men with skin types I to III. We observed a greater-than-expected number of positive patch-test reactions to para-phenylenediamine. We suggest that patch testing and photopatch testing of individuals may be useful adjuncts in the assessment of CAD.

摘要

背景

慢性光化性皮炎（CAD）是一种罕见的光敏性疾病，其流行病学数据很少。

目的

评估 25 年来光斑贴和斑贴试验的人口统计学数据和结果。

方法

对 1993 年至 2009 年 CAD 患者的病历进行回顾性分析。

结果

40 例患者的平均年龄为 57.8 岁，27 例（67.5%）为男性。12 例（30%）患者的皮肤类型为 I 型和 II 型，17 例（42.5%）患者的皮肤类型为 V 型和 VI 型。9 例（22.5%）患者年龄小于 50 岁，其中 4 例（44.4%）为男性。这 9 例患者中有 1 例（11.1%）患者的皮肤类型为 I 型，4 例（44.4%）患者的皮肤类型为 V 型和 VI 型。在斑贴试验中，卡巴混合物和对苯二胺是最常见的两种阳性试剂。在光斑贴试验中，防晒霜、植物及其衍生物是最常见的阳性试剂。