Department of Dermatology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Am J Trop Med Hyg. 2024 Apr 16;110(6):1276-1278. doi: 10.4269/ajtmh.23-0720. Print 2024 Jun 5.
Parthenium hysterophorus is the commonest cause of plant dermatitis in India. It classically causes airborne contact dermatitis (ABCD), characterized by pruritic, eczematous, and lichenified lesions involving predominantly the face and flexural areas. Over time, however, a transition to chronic actinic dermatitis (CAD) pattern, with prominent involvement of sun-exposed sites, may occur. Management involves strict protective measures and topical and oral corticosteroids or immunomodulatory agents but often leads to only limited success. We report a patient with a chronic and extensive mixed ABCD-CAD pattern of parthenium dermatitis recalcitrant to conventional treatment, with rapid resolution after initiation of treatment with tofacitinib.
豚草是印度最常见的植物性皮炎病因。它可引起典型的空气传播接触性皮炎（ABCD），表现为瘙痒、湿疹样和苔藓样皮损，主要累及面颈部和屈侧。然而，随着时间的推移，可能会向慢性光化性皮炎（CAD）模式转变，表现为暴露部位明显受累。治疗包括严格的防护措施和局部及口服皮质类固醇或免疫调节剂，但往往只能取得有限的疗效。我们报告了一例豚草性皮炎患者，其表现为慢性、广泛的 ABCD-CAD 混合模式，对常规治疗反应不佳，而在开始使用托法替尼治疗后迅速缓解。
